- A colony is established on Roanoke Island by Ralph Lane and Richard Greenville and 108 followers. They construct Fort Raleigh. (BES)
- The Roanoke colony is abandoned and the settlers return to England with Sir Francis Drake. (BES)
- John White and 120 settlers attempt to colonize Roanoke Island again. Food is in short supply, so John White returns to England in the hope of procuring some.
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